Review Article Orthobiologics in Orthopedic Cases
Orthobiologics in Orthopedic Cases
Keywords:
Orthobiologics, Musculoskeletal injuriesAbstract
Orthobiologics are biological substances, which are obtained from naturally occurring substances in the body. Musculoskeletal
injuries, broken bones, and torn muscles, tendons, and ligaments are helped by speedier healing. These contemporary biologics
have undergone tremendous evolution and have a significant impact on orthopedic surgical practice. These biologics are available in diversified form such as bone grafts, autologous blood injection, platelet-rich plasma, and various stem cells therapy obtained from bone marrow, amnios, or fat tissue. Each of these biologic substances has some advantages and disadvantages, which would be further elaborated in this article. The purpose of this article is to provide an overview of the reasons for utilizing
orthobiologics, the orthobiologics that are presently accessible, as well as their application in different orthopedic situations.
References
Chu CR, Rodeo S, Bhutani N, Goodrich LR, Huard J,
Irrgang J, et al. Optimizing clinical use of biologics in
orthopaedic surgery: Consensus recommendations from the
AAOS/NIH U-13 conference. J Am Acad Orthop Surg
;27:e50-63.
Obana KK, Schallmo MS, Hong IS, Ahmad CS, Moorman CT,
Trofa DP, et al. Current trends in orthobiologics: An 11-year
review of the orthopaedic literature. Am J Sports Med
;50:3121-9.
Zwingenberger S, Nich C, Valladares RD, Yao Z, Stiehler M,
Goodman SB. Recommendations and considerations for the use
of biologics in orthopedic surgery. BioDrugs 2012;26:245-56.
Moreno-Garcia A, Rodriguez-Merchan EC, Rodriguez-
Merchan EC. Orthobiologics: nt role in orthopedic surgery and
traumatology. Arch Bone Jt Surg 2022;10:536-42.
Sampson DO, Vincent MS, Aufiero D, Botto-van Bemden A.
Orthobiologics: A new frontier for musculoskeletal disease.
J Stem Cell Res Transplant 2014;1:1005.
Solanki K, Shanmugasundaram S, Shetty N, Kim SJ. Articular
cartilage repair and joint preservation: A review of the
current status of biological approach. J Clin Orthop Trauma
;22:101602.
Published
How to Cite
Issue
Section
Copyright (c) 2023 Journal of Bones & Muscles Health
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.