Original Article The Effect of Steroid in the Treatment of Simple Bone Cysts in Comparison with Autogenous Bone Marrow Injection

Management of bone cysts with steroids

Authors

  • Makesh Shah Associate Professor, Department of Orthopedics, Smt. B K Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth, Vadodara, Gujarat, India.
  • Ashutosh Arvind Ajri Consultant-Shoulder, Knee and Sports Injuries, Aadhya Orthopedic and Physiotherapy Care, Sancheti Hospital, Pune, Maharashtra, India

Keywords:

Autogenous bone marrow injection, simple bone cyst, steroid injection

Abstract

Background: Simple bone cysts (SBC) are well-known lesions; however, there is currently no cure for them. Studies using a
common treatment technique – steroid injection – reported results that were quite diverse from one another. The outcomes of patients
with pathological fractures who were not on any treatment were evaluated in comparison to the steroid injection method. Materials
and Methods: A total of 44 patients had steroid injection therapy (Group – I) and 38 were treated with autogenous bone marrow
injection (ABMI). For comparisons, Capanna’s plain radiographic evaluation criteria were applied, and magnetic resonance imaging
(MRI) was utilized. The outcomes were graded in accordance with MRI and X-ray findings. Results: The first and most important
finding was that the majority of ABMI patients responded well following their initial injection. We discovered that the majority of
patients fell within the range of 5 months–1 year, taking into consideration the time between the start of conservative treatment and
the mechanical repair of the cyst (CI lower than 3 and cortical width lower than 2 mm). Conclusion: Failure after a steroid injection
is possible, and healing before the third injection only rarely happens, ABMI is a straightforward, cost-free procedure that works on
both active and dormant cysts, and in the majority of cases, after the initial injection, certain symptoms of healing appear.

 

 

Author Biographies

Makesh Shah, Associate Professor, Department of Orthopedics, Smt. B K Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth, Vadodara, Gujarat, India.

 

 

 

Ashutosh Arvind Ajri, Consultant-Shoulder, Knee and Sports Injuries, Aadhya Orthopedic and Physiotherapy Care, Sancheti Hospital, Pune, Maharashtra, India

 

 

 

References

REFERENCES

Cohen J. Simple bone cysts. Studies of cyst fluid in six

cases with a theory of pathogenesis. J Bone Joint Surg Am

;42-A:609-16.

Zhao JG, Wang J, Huang WJ, Zhang P, Ding N, Shang J.

Interventions for treating simple bone cysts in the long bones of

children. Cochrane Database Syst Rev 2017;2017:CD010847.

Deventer N, Deventer N, Gosheger G, de Vaal M, Vogt B,

Budny T. Current strategies for the treatment of solitary and

aneurysmal bone cysts: A review of the literature. J Bone

Oncol 2021;30:100384.

Zhang P, Zhu N, Du L, Zheng J, Hu S, Xu B. Treatment of

simple bone cysts of the humerus by intramedullary nailing

and steroid injection. BMC Musculoskelet Disord 2020;21:70.

Flont P, Kolacinska-Flont M, Niedzielski K. Factors predictive

of positive response to steroid therapy in simple bone cysts: An

old trick that still works. Int Orthop 2013;37:1519-25.

Hashemi-Nejad A, Cole WG. Incomplete healing of simple

bone cysts after steroid injections. J Bone Joint Surg Br

;79:727-30.

Rahman MA, El Masry AM, Azmy SI. Review of 16 cases

Table 2: Success rates comparison based on MRI findings

Rades Steroid group ABMI group P‑value

Success: n=24 Failure: n=20 Success: n=29 Failure: n=9

Number Percent Number Percent

Healed 6 0 23 0 0.03

With residual 18 0 6 0 0.04

Recurrent 0 10 0 5 0.06

Persistent 0 10 0 4 0.06

ABMI: Autogenous bone marrow injection, MRI: Magnetic resonance imaging

Shah and Ajri: Management of bone cysts with steroids

Journal of Bones and Muscles Health • Vol 1 • Issue 1 • 2023

of aneurysmal bone cyst in the proximal femur treated by

extended curettage and cryosurgery with reconstruction using

autogenous nonvascularized fibula graft. J Orthop Surg (Hong

Kong) 2018;26:2309499018783905.

Zamzam MM, Abak AA, Bakarman KA, Al-Jassir FF,

Khoshhal KI, Zamzami MM. Efficacy of aspiration and

autogenous bone marrow injection in the treatment of simple

bone cysts. Int Orthop 2009;33:1353-8.

Datta NK, Das KP, Alam MS, Kaiser MS. Management of

unicameral bone cyst by using freeze dried radiation sterilized

bone allograft impregnate with autogenous bone marrow.

Mymensingh Med J 2014;23:512-9.

Ulici A, Balanescu R, Topor L, Barbu M. The modern treatment

of the simple bone cysts. J Med Life 2012;5:469-73.

Docquier PL, Delloye C. Treatment of aneurysmal bone cysts

by introduction of demineralized bone and autogenous bone

marrow. J Bone Joint Surg Am 2005;87:2253-8.

Pradel W, Eckelt U, Lauer G. Bone regeneration after

enucleation of mandibular cysts: comparing autogenous grafts

from tissue-engineered bone and iliac bone. Oral Surg Oral

Med Oral Pathol Oral Radiol Endod 2006;101:285-90.

Hunt KJ, Bergeson A, Coffin CM, Randall RL. Percutaneous

curettage and bone grafting for humeral simple bone cysts.

Orthopedics 2009;32:89.

Cho HS, Seo SH, Park SH, Park JH, Shin DS, Park IH.

Minimal invasive surgery for unicameral bone cyst using

demineralized bone matrix: A case series. BMC Musculoskelet

Disord 2012;13:134.

Hou HY, Wu K, Wang CT, Chang SM, Lin WH, Yang RS.

Treatment of unicameral bone cyst: A comparative study of

selected techniques. J Bone Joint Surg Am 2010;92:855-62.

Published

01-07-2023

How to Cite

Shah, M. D. ., & Ajri, A. A. . (2023). Original Article The Effect of Steroid in the Treatment of Simple Bone Cysts in Comparison with Autogenous Bone Marrow Injection: Management of bone cysts with steroids. Journal of Bones &Amp; Muscles Health, 1(1), 13–16. Retrieved from https://portal.jbmh.in/index.php/ins/article/view/17

Issue

Section

Original Article